
If you love salmon but are tired of the same old preparation methods, this 20-minute garlic knot salmon recipe is about to change your weeknight dinner routine. As someone who doesn’t often cook meat at home, salmon is an exception I make frequently. It’s quick, healthy, and versatile, which makes it a perfect choice for any occasion. The combination of tender, flaky salmon with buttery garlic knots is irresistible!
Whether you’re cooking for yourself or entertaining guests, this recipe will satisfy everyone. The buttery, garlicky breadcrumbs and savory Parmesan take the flavor to the next level, making this dish both easy to prepare and absolutely delicious. It’s a great way to add variety to your meal rotation and keep things exciting in the kitchen.
Perfect for a busy evening, this dish comes together in under 20 minutes with minimal prep time. The roasted salmon fillets are topped with a mouthwatering mixture of garlic butter, crispy breadcrumbs, and Parmesan, creating a flavorful crust that enhances the natural richness of the fish. Plus, a squeeze of fresh lemon and a sprinkle of parsley add the finishing touch for a fresh, zesty flavor.
Why You’ll Love This Recipe
- Quick and Easy: It’s a fast recipe that comes together in under 20 minutes.
- Flavorful: Garlic butter, breadcrumbs, and Parmesan add a crispy, savory topping to the salmon.
- Versatile: This dish is perfect for weeknight dinners or entertaining guests.
- Minimal Cleanup: Roasting the salmon keeps the cleanup simple and hassle-free.

Ingredients Overview
The ingredients for this recipe are simple yet packed with flavor. You’ll need fresh salmon fillets, melted butter, garlic, panko breadcrumbs, and Parmesan cheese. These ingredients come together to create a rich, buttery topping that perfectly complements the natural flavors of the fish. Fresh parsley adds a touch of color and freshness, while a squeeze of lemon brightens up the dish. If you’re using frozen salmon, be sure to thaw it completely before baking.
How to Make the Recipe
Step 1: Preheat the oven to 425°F (220°C). While the oven is heating up, prepare your baking dish. Add half of the melted garlic butter mixture to the dish, ensuring it’s spread evenly across the bottom to create a flavorful base for the salmon fillets.
Step 2: In a small bowl, combine the remaining garlic butter with panko breadcrumbs and finely grated Parmesan. Stir until everything is well incorporated. This mixture will create a crispy, cheesy topping for the salmon, adding both texture and flavor.
Step 3: Pat the salmon fillets dry with paper towels to remove any excess moisture. Season them generously with kosher salt. Place the fillets in the prepared baking dish, skin-side down if your fillets have skin, ensuring they sit without overlapping.
Step 4: Spoon the breadcrumb mixture generously over each salmon fillet. Press down lightly to help the breadcrumbs stick and form an even crust. If any breadcrumbs fall off, simply scoop them up and pile them back on top for an even coating.
Step 5: Bake the salmon for 12 to 16 minutes, depending on the thickness of your fillets. Check for doneness by gently flaking the salmon with a fork. The internal temperature should reach around 135°F for medium doneness, but feel free to adjust according to your preference.
Step 6: Once the salmon is cooked, remove the fillets from the oven and transfer them to plates. Drizzle any remaining garlic butter from the baking dish over the top of the salmon. Garnish with freshly minced parsley and serve with lemon wedges for a bright, zesty finish.

Tips for the Best Recipe
- Defrosting: If using frozen salmon, make sure to thaw it completely before cooking. This ensures even cooking and prevents excess moisture in the dish.
- Even Fillets: Try to select salmon fillets of similar size to ensure they cook evenly. This way, you won’t have to worry about some fillets cooking faster than others.
- Breadcrumbs: Be generous with the breadcrumb mixture. Press it down lightly on the salmon to ensure it sticks, creating that perfect crispy texture.
- Skin Removal: If you prefer not to eat the skin, simply slide a metal spatula between the skin and the fillet to remove it after cooking. The skin crisps up beautifully in this recipe, but it’s totally optional.
Variations to Try
- Add Herbs: Try adding some fresh herbs like thyme or rosemary to the breadcrumb mixture for an aromatic twist.
- Spicy Option: Add a pinch of red pepper flakes to the garlic butter for a little heat.
- Cheese Variety: Swap the Parmesan for a different cheese like Asiago or Pecorino for a new flavor profile.
Frequently Asked Questions (FAQs)
- Can I use frozen salmon fillets? Yes, just make sure to thaw the fillets completely before cooking for even cooking and texture.
- Can I remove the skin from the salmon? Absolutely! While the skin crisps up nicely in this recipe, you can remove it by gently sliding a spatula between the skin and the flesh.
- How do I know when the salmon is done? For medium doneness, the internal temperature should reach about 135°F (57°C). The salmon should flake easily with a fork.
- Can I make this dish ahead of time? While salmon is best fresh, you can prepare the breadcrumb topping ahead of time and store it in the fridge. Just add it to the fillets before baking.
- What can I serve with garlic knot salmon? This dish pairs perfectly with roasted vegetables, a simple salad, or mashed potatoes.

How to Store and Reheat
Store any leftover garlic knot salmon in an airtight container in the refrigerator for up to 2 days. To reheat, place the fillets in a preheated oven at 350°F (175°C) for 5-7 minutes until warmed through. Alternatively, you can reheat the salmon in the microwave for a few minutes, but be careful not to overcook it.
Conclusion
This garlic knot salmon recipe has quickly become a family favorite in my house. It’s easy, flavorful, and perfect for a busy weeknight meal. The crispy breadcrumbs, garlic butter, and Parmesan create a deliciously indulgent topping that complements the tender salmon beautifully. Whether you’re cooking for one or serving guests, this dish is sure to impress.
If you love quick and tasty meals, don’t forget to follow me on Pinterest at Ava Foodie for more delicious recipes!